In the January 2018 volume of The ANNALS, special editors Andrew Reamer (George Washington University), Julia Lane (NYU), Ian Foster (University of Chicago), and David Ellwood (Harvard Kennedy School) bring together experts from across disciplines to outline the infrastructures that will need to be built to make sure data providers and empirical researchers can best serve national policy needs. The volume is organized around three topics: privacy and confidentiality, data providers, and comprehensive strategies.